Koshiyama M, Fujii H, Konishi M, Nanno H, Hayashi M, Tauchi K, Yoshida M
Department of Obstetrics and Gynecology, Tenri Hospital, Nara, Japan.
Eur J Obstet Gynecol Reprod Biol. 1999 Feb;82(2):227-9. doi: 10.1016/s0301-2115(98)00165-1.
We experienced the case of a clear cell carcinoma of the ovary arising from an endometrial cyst, which started to produce parathyroid hormone-related protein (PTH-rP) in a recurrent tumor, thus inducing hypercalcemia. Using immunohistochemical analysis, we demonstrated that the primary carcinoma was immunonegative for PTH-rP, but that the recurrent carcinoma was strongly immunopositive for PTH-rP.