Leibing E, Pfingsten M, Bartmann U, Rueger U, Schuessler G
Department of Psychosomatics, Psychotherapy, Georg-August-University, Goettingen, Germany.
Clin J Pain. 1999 Mar;15(1):58-66. doi: 10.1097/00002508-199903000-00009.
This trial was performed to evaluate the efficacy of an adjunctive cognitive-behavioral treatment compared with rheumatological treatment alone in unselected rheumatoid arthritis outpatients.
A prospective randomized control design was used. Change in medication during treatment was controlled by matching therapy- and control-group subjects according to this change in medication, sex, age, duration of disease, and functional class.
A rheumatological outpatient clinic, University of Goettingen, Germany.
Fifty-five consecutive outpatients with a diagnosis of rheumatoid arthritis (age 52.7 years, 74.5% female, duration of disease 9.4 years) finished the study.
Subjects received routine care by the rheumatologists and routine medical treatment. Cognitive-behavioral treatment subjects (n = 19) received adjunctive standardized cognitive-behavioral group treatment with 12 weekly sessions.
Outcome measures included disease activity variables, pain variables (pain intensity, affective pain), psychological symptoms, and coping.
Subjects mostly demonstrated an increasing disease activity during treatment; change in medication during treatment was necessary in some patients. In the cognitive-behavioral treatment group the course of rheumatoid arthritis seemed less progressive than in the control group. The core effects of cognitive-behavioral treatment pertain more to improved coping, emotional stabilization, and reduced impairment than to reduced pain intensity. Passive, emotion-focused coping, helplessness, depression, anxiety, affective pain, and fluctuation of pain are reduced, "Acceptance of Illness" is improved.
Cognitive-behavioral therapy has proven an effective adjunct to standard treatment of rheumatoid arthritis outpatients. These effects were shown in an unselected sample with increasing disease activity and with comparable changes in medication during treatment. We recommend cognitive-behavioral treatment as an desirable adjunct to standard medical treatment of rheumatoid arthritis.
本试验旨在评估在未经过挑选的类风湿性关节炎门诊患者中,辅助性认知行为疗法相较于单纯的风湿病治疗的疗效。
采用前瞻性随机对照设计。治疗期间的用药变化通过根据用药变化、性别、年龄、病程和功能分级对治疗组和对照组受试者进行匹配来控制。
德国哥廷根大学的风湿病门诊。
55名连续诊断为类风湿性关节炎的门诊患者(年龄52.7岁,74.5%为女性,病程9.4年)完成了研究。
受试者接受风湿病学家的常规护理和常规药物治疗。认知行为治疗组(n = 19)接受辅助性标准化认知行为团体治疗,每周一次,共12次。
观察指标包括疾病活动变量、疼痛变量(疼痛强度、情感性疼痛)、心理症状和应对方式。
受试者在治疗期间大多表现出疾病活动增加;部分患者在治疗期间需要改变用药。在认知行为治疗组中,类风湿性关节炎的病程似乎比对照组进展得更慢。认知行为治疗的核心作用更多地在于改善应对方式、情绪稳定和减少损伤,而非降低疼痛强度。被动的、以情绪为中心的应对方式、无助感、抑郁、焦虑、情感性疼痛和疼痛波动减少,“对疾病的接受度”提高。
认知行为疗法已被证明是类风湿性关节炎门诊患者标准治疗的有效辅助手段。这些效果在一个未经过挑选的样本中得到体现,该样本疾病活动增加且治疗期间用药有类似变化。我们推荐将认知行为治疗作为类风湿性关节炎标准药物治疗的理想辅助手段。