Tarasova L N, Kudriashova Iu I
Vestn Oftalmol. 1999 Jan-Feb;115(1):29-31.
Pure corneal ulcers can be localized at the periphery and in the center. Peripheral ulcers are bilateral in 66% and multifocal in 48% cases. They are combined with local vasculitis of perilimbic vessels of the conjunctiva. In 84% cases the disease occurred in patients with connective tissue and articular diseases. Clinical picture of the peripheral corneal ulcer differs from Mourene's phagodenic ulcer. Central corneal ulcers are bilateral in 40% patients, are associated with primary and secondary "dry eye" syndrome in Sjogren's disease, rheumatoid arthritis, systemic vasculitis, Behçet's disease, and in 18% patients with cicatricial deformation of the conjunctiva after Stevens-Johnson's syndrome, trachoma, and chemical burns of the eyes. Pure corneal ulcers run a chronic relapsing course, complicated in one-fourth of patients by corneal perforation and secondary infections.