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[经阴道超声检查在绝经后出血评估中的评级]

[Rating of transvaginal sonography in the evaluation of postmenopausal bleeding].

作者信息

Gerber B, Krause A, Kuelz T, Quasmeh A, Reimer T, Friese K

机构信息

Universitäts-Frauenklinik Rostock.

出版信息

Zentralbl Gynakol. 1999;121(3):143-8.

Abstract

OBJECTIVE

The purpose of this study was to evaluate transvaginal ultrasonography (TVS) in differential diagnosis of vaginal bleedings in postmenopausal patients.

MATERIAL AND METHODS

Between January 1990 and December 1996, 1198 postmenopausal patients with vaginal bleedings were sent to our clinic for a histological evaluation. Eight hundred and seventy-nine patients (73.4%) were preoperatively scanned by transvaginal probe, and endometrial thickness (< 5, 5-7, 8-10, > 10 mm) was measured.

RESULTS

Atrophy was found in 46.3%, endometrial polyps in 19.8%, endometrial cancer in 17.5%, and hyperplasia in 6.7%. An endometrial thickness of lower than 5 mm (p < 0.0001) was shown in TVS patients with atrophy in 71%, with endometrial polyps in 10.9%, with endometrial cancer in 3.9% and hyperplasia in 6.8%. In 55.2% of these eases with endometrial cancer the preoperatively estimated thickness was 10 mm or more. The additionally morphologic examination in cases with an endometrium smaller than 5 mm was false positive in 75% (9/12). Thus an endometrial thickness of > 5 mm had a sensitivity of 92.5%, specificity of 71.0%, positive and negative predictive value of 75.6, respectively 90.9% for the detection of endometrial pathology.

CONCLUSIONS

TVS allows the detection of an endometrial pathology in the vast majority of patients with postmenopausal bleedings. In cases with a single postmenopausal bleeding and an endometrium smaller than 5 mm we recommend expectative procedures with repeated ultrasound examination of the endometrium.

摘要

目的

本研究旨在评估经阴道超声检查(TVS)在绝经后患者阴道出血鉴别诊断中的应用。

材料与方法

1990年1月至1996年12月期间,1198例绝经后阴道出血患者被送至我院进行组织学评估。其中879例患者(73.4%)术前接受经阴道探头扫描,并测量子宫内膜厚度(<5、5 - 7、8 - 10、>10 mm)。

结果

发现萎缩占46.3%,子宫内膜息肉占19.8%,子宫内膜癌占17.5%,增生占6.7%。TVS检查显示,子宫内膜厚度低于5 mm的患者中,萎缩占71%,子宫内膜息肉占10.9%,子宫内膜癌占3.9%,增生占6.8%。在这些子宫内膜癌病例中,术前估计厚度为10 mm或以上的占55.2%。子宫内膜小于5 mm的病例中,额外的形态学检查假阳性率为75%(9/12)。因此,子宫内膜厚度>5 mm对子宫内膜病变检测的敏感性为92.5%,特异性为71.0%,阳性预测值和阴性预测值分别为75.6%和90.9%。

结论

TVS能够在绝大多数绝经后出血患者中检测出子宫内膜病变。对于单一绝经后出血且子宫内膜小于5 mm的病例,我们建议采用期待性治疗方案,并对子宫内膜进行重复超声检查。

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