对杏仁核进行电刺激会增加诱发的脑桥-膝状体-枕叶波的振幅。

Electrical stimulation of the amygdala increases the amplitude of elicited ponto-geniculo-occipital waves.

作者信息

Deboer T, Ross R J, Morrison A R, Sanford L D

机构信息

Department of Animal Biology, School of Veterinary Medicine, Philadelphia, PA 19104-6045, USA.

出版信息

Physiol Behav. 1999 Mar;66(1):119-24. doi: 10.1016/s0031-9384(98)00281-9.

DOI:10.1016/s0031-9384(98)00281-9

PMID:10222483

Abstract

The amygdala projects massively via its central nucleus (CNA) into brain stem regions involved in alerting and ponto-geniculo-occipital (PGO) wave generation. Electrical stimulation of CNA is known to enhance the acoustic startle response (ASR) and influence spontaneous PGO waves. The role of the amygdala in the modulation of ASR and elicited PGO waves (PGOE) was investigated in albino rats. Electrically stimulating CNA within 25 ms prior to an auditory stimulus enhanced ASR and PGOE amplitude in a similar way, with the largest response occurring when the electrical and auditory stimuli were given simultaneously. The data suggest that CNA modulates alerting mechanisms.

摘要

杏仁核通过其中央核（CNA）大量投射到参与警觉和脑桥-膝状体-枕叶（PGO）波产生的脑干区域。已知对CNA进行电刺激可增强听觉惊吓反应（ASR）并影响自发PGO波。在白化大鼠中研究了杏仁核在调节ASR和诱发PGO波（PGOE）中的作用。在听觉刺激前25毫秒内对CNA进行电刺激，以类似的方式增强了ASR和PGOE的幅度，当电刺激和听觉刺激同时给予时反应最大。数据表明CNA调节警觉机制。