Crespel A, Coubes P, Baldy-Moulinier M
Service d'Explorations Neurologiques et d'Epileptologie, Hôpital Gui de Chauliac, Montpellier.
Rev Neurol (Paris). 1999 Feb;155(2):131-4.
The facilitating effect of awakening and sleep deprivation on seizure production and EEG abnormalities is characteristic of idiopathic generalized epilepsies (IGE). This effect is particularly patent in awakening epilepsy. Paroxysmal events occurring in non-REM sleep, related to spindle production during transitional periods or awakening are characteristic of IGE. Because IGEs are particularly sensitive to sleep, sleep deprivation, and awakening, the association of these three conditions is particularly helpful in exploration protocols, especially when no wakefulness abnormalities are seen on the EEG. These observations in IGE suggest a dysfunction of awakening control systems. Awakening epilepsies may be differentiated from sleep-induced seizures observed in other IGE and in partial epilepsies.
觉醒和睡眠剥夺对癫痫发作及脑电图异常的促进作用是特发性全身性癫痫(IGE)的特征。这种作用在觉醒性癫痫中尤为明显。非快速眼动睡眠期出现的阵发性事件,与过渡期或觉醒期的纺锤波产生有关,是IGE的特征。由于IGE对睡眠、睡眠剥夺和觉醒特别敏感,这三种情况的关联在探索性检查方案中特别有用,尤其是当脑电图未发现清醒期异常时。IGE的这些观察结果提示觉醒控制系统存在功能障碍。觉醒性癫痫可与在其他IGE及部分性癫痫中观察到的睡眠诱发癫痫相鉴别。