Sasahashi N, Ando F, Okamoto F, Hanada M, Yamanaka K, Kameyama T, Nishigaki Y, Hirose K, Kambara A, Sakazaki H, Suzuki T, Makino S
Department of Cardiovascular Surgery, Hyogo Kenritsu Amagasaki Hospital, Japan.
Kyobu Geka. 1999 Apr;52(4):269-73.
Between 1975 and 1998, 27 patients aged 3 months to 14 years underwent replacement of the aortic, mitral, tricuspid, and pulmonary valves. Five different types of prosthetic valves were used; three were mechanical valves and two were bioprosthetic valves. There were 3 hospital deaths. Among the 24 survivors there were 4 late deaths. Arrhythmia requiring pacemaker implantation occurred in 2 cases after AVR and TVR. Thromboembolic events occurred in 3 patients, all with mechanical valves in pulmonary position. Infective endocarditis occurred in 1 patient after PVR with a mechanical valve. No bleeding complication occurred among the patients on a regimen of Coumadin and Dipyridamole. Two patients, both with Hancock bioprosthesis, required a second valve replacement on account of severely calcified changes. Mechanical valves in left side heart had a satisfactory long-term performance. One patient who had undergone MVR for congenital parachute mitral valve received reoperation for growth. A larger sized prosthetic valve should be used at the first replacement, and special procedures including supra-annular positioning or annular augmentation are recommended for MVR or AVR respectively.
1975年至1998年间,27例年龄在3个月至14岁的患者接受了主动脉瓣、二尖瓣、三尖瓣和肺动脉瓣置换术。使用了五种不同类型的人工瓣膜;三种是机械瓣膜,两种是生物瓣膜。有3例医院死亡病例。在24名幸存者中有4例晚期死亡。在主动脉瓣置换术和三尖瓣置换术后,有2例患者发生需要植入起搏器的心律失常。3例患者发生血栓栓塞事件,均为肺动脉位置植入机械瓣膜者。1例肺动脉瓣置换术后植入机械瓣膜的患者发生感染性心内膜炎。接受华法林和双嘧达莫治疗的患者未发生出血并发症。两名均植入汉考克生物瓣膜的患者因严重钙化改变需要再次进行瓣膜置换。左侧心脏的机械瓣膜长期性能良好。1例因先天性降落伞样二尖瓣接受二尖瓣置换术的患者因生长发育接受了再次手术。首次置换时应使用更大尺寸的人工瓣膜,二尖瓣置换术或主动脉瓣置换术分别建议采用包括瓣环上定位或瓣环扩大在内的特殊手术方法。