Hoffer E K, Cosgrove J M, Levin D Q, Herskowitz M M, Sclafani S J
Department of Radiology, Kings County Hospital Center, Brooklyn, New York, USA.
J Vasc Interv Radiol. 1999 Apr;10(4):413-20. doi: 10.1016/s1051-0443(99)70058-8.
To compare the efficacy of radiologic guided placement of percutaneous gastrojejunostomy (PGJ) and percutaneous endoscopic gastrostomy (PEG).
Patients were randomized to PGJ (n = 66) or PEG (n = 69). Indications for gastrostomy were need for prolonged enteral nutrition (97%) or gastrointestinal decompression (3%), with etiologies of neurologic impairment (81%), head and neck neoplasm (12%), bowel obstruction (3%), or other (4%). Mean follow-up was 202 days and 30-day follow-up was obtained for 85% of patients.
PEG was successful in 63 of 69 (91%) patients, while PGJ established access in all of 66 attempts (100%) (P = .014). Average procedural time was 53 minutes for PGJ and 24 minutes for PEG (P = .001). At 30-day follow-up, there were 33 and 45 complications in the PGJ and PEG groups, respectively. This difference was due to the greater incidence of pneumonia in the PEG group (P = .013). Long-term tube-related complications occurred with 17 PGJs and four PEGs (P = .007). The PGJ cost more than PEG, but this advantage was offset by the cost of complications.
PGJ had higher success rate and fewer complications, due to a lower incidence of pneumonia. PEG took less time to perform, cost less, and required less tube maintenance.
比较放射引导下经皮胃空肠造口术(PGJ)与经皮内镜下胃造口术(PEG)的疗效。
患者被随机分为PGJ组(n = 66)或PEG组(n = 69)。胃造口术的适应证为需要长期肠内营养(97%)或胃肠减压(3%),病因包括神经功能障碍(81%)、头颈部肿瘤(12%)、肠梗阻(3%)或其他(4%)。平均随访时间为202天,85%的患者获得了30天的随访结果。
PEG组69例患者中有63例成功(91%),而PGJ组66次尝试均成功建立通道(100%)(P = 0.014)。PGJ的平均操作时间为53分钟,PEG为24分钟(P = 0.001)。在30天随访时,PGJ组和PEG组分别有33例和45例并发症。这种差异是由于PEG组肺炎发生率更高(P = 0.013)。长期与导管相关的并发症在17例PGJ和4例PEG中出现(P = 0.007)。PGJ的费用高于PEG,但这一优势被并发症的费用所抵消。
PGJ成功率更高且并发症更少,原因是肺炎发生率较低。PEG操作时间更短,成本更低,且导管维护需求更少。