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[Kaposiform HHV-8 negative acroangiodermatitis in chronic venous insufficiency].

作者信息

Krengel S, Goerdt S, Krüger K, Schnitzler P, Geiss M, Tebbe B, Blume-Peytavi U, Orfanos C E

机构信息

Hautklinik und Poliklinik, Universitätsklinikum Benjamin Franklin, Freie Universität Berlin.

出版信息

Hautarzt. 1999 Mar;50(3):208-13. doi: 10.1007/s001050050891.

Abstract

A 76-year-old female patient developed severe manifestations of a kaposi-like acroangiodermatitis (so-called Mali's disease) due to chronic venous insufficiency of the lower extremities. The patient presented with large areas of confluent, violaceous or brown-black papules on both lower legs. Histologically, proliferation of thick-walled capillaries was seen in the upper dermis consisting of fully differentiated endothelial cells, as shown by immunohistochemistry. In contrast to true Kaposi's sarcoma, human-herpes-virus-8 DNA could not be detected by polymerase-chain-reaction in this condition. We review the diagnostic criteria used to distinguish between acroangiodermatitis, also called pseudo-Kaposi's sarcoma, and the true Kaposi's sarcoma.

摘要

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