Sharma D C, Sharma P, Sharma S
Department of Biochemistry, SMS Medical College, Jaipur.
Indian J Physiol Pharmacol. 1997 Jul;41(3):285-8.
About 50 mg of silver leaf (metallic silver) was given daily by mouth to 30 healthy volunteers for 20 days. A statistically significant hypophospholipidemic, hypotriglyceridemic, hypocholesterolemic and hypoglycemic effect was observed. This was accompanied by a less marked fall in total lipids and significant rise in HDL-cholesterol. In addition, a decrease in plasma enzymes - alkaline phosphatase (ALP), glutamate oxaloacetate transaminase (GOT), glutamate pyruvate transaminase (GPT), creatine phosphokinase (CPK), gamma glutamyl transpeptidase (GGT) and lactate dehydrogenase (LDH) was noted. This was statistically significant for all enzymes except CPK. The safety of ingested silver foil is indicated by absence of pathology in urine and unaltered levels of protein and albumin in the plasma. These observations suggest that silver could be beneficial in conditions like diabetes mellitus, obesity and atherosclerosis.
30名健康志愿者连续20天每天口服约50毫克银叶(金属银)。观察到有统计学意义的降磷脂、降甘油三酯、降胆固醇和降血糖作用。同时,总脂质有不太明显的下降,高密度脂蛋白胆固醇显著升高。此外,还注意到血浆酶——碱性磷酸酶(ALP)、谷氨酸草酰乙酸转氨酶(GOT)、谷氨酸丙酮酸转氨酶(GPT)、肌酸磷酸激酶(CPK)、γ-谷氨酰转肽酶(GGT)和乳酸脱氢酶(LDH)有所下降。除CPK外,所有酶的下降均具有统计学意义。摄入银箔的安全性体现在尿液无病变以及血浆中蛋白质和白蛋白水平未改变。这些观察结果表明,银可能对糖尿病、肥胖症和动脉粥样硬化等病症有益。