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在给予氯丙嗪期间,诱发电位晚期慢成分对光的倍增。

Multiplication of the late slow component of the evoked potential to light during chlorpromazine administration.

作者信息

Shumilina A I, Burza Z B

出版信息

Neurosci Behav Physiol. 1976 Jan-Mar;7(1):20-3. doi: 10.1007/BF01148743.

DOI:10.1007/BF01148743
PMID:1027995
Abstract

In experiments on unanesthetized rabbits with electrodes permanently implanted into various brain formations the effect of chlorpromazine was studied on the phenomenon of multiplication of the late slow component of the evoked potential to flashes of light applied at a frequency of 1 Hz, some of which were given simultaneously with electric shocks to the hind limb. Chlorpromazine was found to reduce the multiplication of the slow component to flashes applied without electric shocks and to facilitate the reduplication of this component to flashes applied along with the nociceptive stimulation. In the discussion of the results a role of adrenergic structures is postulated in the formation of the defensive action acceptor, one of the most important and crucial mechanisms of the functional system.

摘要

在将电极永久植入各种脑结构的未麻醉兔子实验中,研究了氯丙嗪对以1Hz频率施加的闪光诱发电位晚期慢成分倍增现象的影响,其中一些闪光与后肢电击同时施加。发现氯丙嗪可减少在无电击情况下施加的闪光的慢成分倍增,并促进该成分在与伤害性刺激一起施加的闪光时的重复。在结果讨论中,假定肾上腺素能结构在防御动作感受器的形成中起作用,防御动作感受器是功能系统最重要和关键的机制之一。

相似文献

1
Multiplication of the late slow component of the evoked potential to light during chlorpromazine administration.在给予氯丙嗪期间,诱发电位晚期慢成分对光的倍增。
Neurosci Behav Physiol. 1976 Jan-Mar;7(1):20-3. doi: 10.1007/BF01148743.
2
[Multiplication of the late slow fluctuation of induced potential to light under conditions of aminazin administration].[在使用氯丙嗪的情况下诱导电位对光的晚期慢波动的倍增]
Biull Eksp Biol Med. 1975 Sep;80(9):3-7.
3
Differential effects of pentobarbital, ethyl alcohol, and chlorpromazine in modifying reticular facilitation of visually evoked responses in the cat.戊巴比妥、乙醇和氯丙嗪对猫视觉诱发电位网状易化作用的不同影响。
Int J Neuropharmacol. 1969 Jan;8(1):61-72. doi: 10.1016/0028-3908(69)90036-7.
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本文引用的文献

1
[Characteristics of conditioned reflex action in dogs following administration of aminazine].[给予氯丙嗪后犬的条件反射活动特征]
Zh Nevropatol Psikhiatr Im S S Korsakova. 1956;56(2):116-20.
2
[Inhibiting effect of aminazine on central effect of pain stimulus].[氯丙嗪对疼痛刺激中枢效应的抑制作用]
Zh Nevropatol Psikhiatr Im S S Korsakova. 1956;56(2):94-103.