Shumilina A I, Burza Z B
Neurosci Behav Physiol. 1976 Jan-Mar;7(1):20-3. doi: 10.1007/BF01148743.
In experiments on unanesthetized rabbits with electrodes permanently implanted into various brain formations the effect of chlorpromazine was studied on the phenomenon of multiplication of the late slow component of the evoked potential to flashes of light applied at a frequency of 1 Hz, some of which were given simultaneously with electric shocks to the hind limb. Chlorpromazine was found to reduce the multiplication of the slow component to flashes applied without electric shocks and to facilitate the reduplication of this component to flashes applied along with the nociceptive stimulation. In the discussion of the results a role of adrenergic structures is postulated in the formation of the defensive action acceptor, one of the most important and crucial mechanisms of the functional system.
在将电极永久植入各种脑结构的未麻醉兔子实验中,研究了氯丙嗪对以1Hz频率施加的闪光诱发电位晚期慢成分倍增现象的影响,其中一些闪光与后肢电击同时施加。发现氯丙嗪可减少在无电击情况下施加的闪光的慢成分倍增,并促进该成分在与伤害性刺激一起施加的闪光时的重复。在结果讨论中,假定肾上腺素能结构在防御动作感受器的形成中起作用,防御动作感受器是功能系统最重要和关键的机制之一。