多中心恶性胶质瘤的影像学发病率。
Radiographic incidence of multicentric malignant gliomas.
作者信息
Djalilian H R, Shah M V, Hall W A
机构信息
Department of Neurosurgery, University of Minnesota Hospital and Clinic, Minneapolis, USA.
出版信息
Surg Neurol. 1999 May;51(5):554-7; discussion 557-8. doi: 10.1016/s0090-3019(98)00054-8.
BACKGROUND
Multicentric malignant gliomas are interesting yet uncommon clinical entities with an unknown rate of occurrence.
METHODS
We reviewed the computed tomography (CT) and magnetic resonance (MR) images of 100 consecutive patients with malignant gliomas to determine the incidence of multicentricity in malignant glial neoplasms.
RESULTS
Five patients had multiple lesions on their initial radiographic study (synchronous lesions) and in four patients multiplicity developed after initial diagnosis (metachronous lesions). MR imaging demonstrated one lesion not seen on CT.
CONCLUSIONS
Because synchronous or metachronous multicentricity was found in 9% of patients with malignant gliomas, treatment delivery should not be based on radiographic imaging without attempting to obtain an accurate diagnosis of the ongoing intracranial process.
背景
多中心性恶性胶质瘤是有趣但不常见的临床实体，其发生率未知。
方法
我们回顾了100例连续的恶性胶质瘤患者的计算机断层扫描（CT）和磁共振（MR）图像，以确定恶性胶质瘤中多中心性的发生率。
结果
5例患者在初次影像学检查时有多个病灶（同步病灶），4例患者在初次诊断后出现多病灶（异时病灶）。磁共振成像显示了一个CT上未发现的病灶。
结论
由于在9%的恶性胶质瘤患者中发现了同步或异时多中心性，因此治疗方案不应仅基于影像学检查，而应尝试对颅内病变进行准确诊断。
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