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间歇性外斜视的过矫负透镜疗法会导致近视吗?

Does overcorrecting minus lens therapy for intermittent exotropia cause myopia?

作者信息

Kushner B J

机构信息

Pediatric Eye and Adult Strabismus Clinic, Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, USA.

出版信息

Arch Ophthalmol. 1999 May;117(5):638-42. doi: 10.1001/archopht.117.5.638.

Abstract

BACKGROUND

Overcorrecting minus lens therapy has been used as a treatment for intermittent exotropia. It is based on the principle that an exotropic deviation will be decreased by stimulating accommodative convergence with additional minus power in spectacles. Because excessive accommodation has been implicated as a cause of myopia, there is theoretical concern that overcorrecting minus lens therapy for exotropia may cause myopia.

OBJECTIVE

To investigate the effect of overcorrecting minus lens therapy for exotropia on the progression of myopia.

DESIGN

A retrospective chart review.

SUBJECTS AND METHODS

Seventy-four patients with intermittent exotropia were treated with overcorrecting minus lens therapy for at least 6 months (6-month treatment group), and a 34-patient subset of them received overcorrecting minus lens therapy for 5 years (5-year treatment group). The mean change in refractive error (spherical equivalent of the fixing eye) of these 2 groups 5 years after initial examination was compared with the mean change in refractive error of a control group of 45 patients with intermittent exotropia who did not receive overcorrecting minus lens therapy.

RESULTS

At the time of initial examination, the mean (+/-SD) refractive error was 0.00 +/- 1.40 diopters (D) in the control group, 0.00 +/- 1.50 D in the study group, and -0.10 +/- 1.50 D in the 5-year study group, all of which were essentially identical. Five years after initial examination, the mean change in refractive error was -1.40 +/- 2.80 D in the control group, -1.52 +/- 1.80 D in the 6-month treatment group, and -1.54 +/- 1.80 D in the 5-year treatment group. These differences in the change in refractive error (myopic shift) were not statistically significant (t test), and the differences are clinically unimportant.

CONCLUSION

Overcorrecting minus lens therapy for intermittent exotropia does not appear to cause myopia.

摘要

背景

过矫负透镜疗法已被用于治疗间歇性外斜视。其基于这样的原理,即通过在眼镜中增加负镜度来刺激调节性集合,从而减少外斜度数。由于过度调节被认为是近视的一个原因,因此理论上担心用于治疗外斜视的过矫负透镜疗法可能会导致近视。

目的

研究过矫负透镜疗法治疗外斜视对近视进展的影响。

设计

回顾性病历审查。

对象与方法

74例间歇性外斜视患者接受过矫负透镜疗法至少6个月(6个月治疗组),其中34例患者的子集接受过矫负透镜疗法5年(5年治疗组)。将这两组患者初次检查后5年屈光不正(注视眼的等效球镜度)的平均变化与45例未接受过矫负透镜疗法的间歇性外斜视对照组患者屈光不正的平均变化进行比较。

结果

初次检查时,对照组平均(±标准差)屈光不正为0.00±1.40屈光度(D),研究组为0.00±1.50 D,5年研究组为 -0.10±1.50 D,三者基本相同。初次检查后5年,对照组屈光不正的平均变化为 -1.40±2.80 D,6个月治疗组为 -1.52±1.80 D,5年治疗组为 -1.54±1.80 D。这些屈光不正变化(近视性偏移)的差异无统计学意义(t检验),且在临床上不重要。

结论

间歇性外斜视的过矫负透镜疗法似乎不会导致近视。

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