Geijer B, Brockstedt S, Lindgren A, Ståhlberg F, Norrving B, Holtås S
Department of Diagnostic Radiology, University Hospital, Lund, Sweden.
Acta Radiol. 1999 May;40(3):255-62. doi: 10.3109/02841859909175551.
To compare conventional MR imaging, echo-planar diffusion-weighted imaging (EP-DWI) and spin-echo diffusion-weighted imaging (SE)-DWI at radiological diagnosis of acute stroke.
Twenty-seven patients (30-85 years old) were examined. Clinical examination was performed before MR imaging. All MR examinations were assessed by an experienced neuroradiologist blinded to clinical findings.
In EP-DWI, every patient had a lesion corresponding to the clinical findings. EP-DWI was used as the gold standard. In conventional PD+T2 imaging, 23/59 focal lesions were interpreted as acute, which was false in 11 lesions, and 36/59 lesions were considered to be old, 6 were in fact acute. Nine acute lesions were only detected retrospectively and 12 acute lesions were not detected at all on PD+T2. SE-DWI including the apparent diffusion coefficient correlated fairly well with EP-DWI but the procedure was impractical.
EP-DWI is reliable for diagnosis of early ischemic stroke, while SE-DWI performs reasonably well. Conventional PD+T2 imaging is not reliable for diagnosis of early ischemia.
比较传统磁共振成像、回波平面扩散加权成像(EP-DWI)和自旋回波扩散加权成像(SE-DWI)在急性脑卒中放射学诊断中的应用。
对27例年龄在30至85岁之间的患者进行检查。在磁共振成像检查前进行临床检查。所有磁共振检查均由一位对临床结果不知情的经验丰富的神经放射科医生进行评估。
在EP-DWI检查中,每位患者均有一个与临床结果相符的病灶。EP-DWI被用作金标准。在传统的质子密度加权成像(PD)加T2加权成像中,59个局灶性病灶中有23个被判定为急性病灶,其中11个为误诊,59个病灶中有36个被认为是陈旧性病灶,而实际上有6个是急性病灶。9个急性病灶仅在回顾性检查中被发现,在PD加T2加权成像中,有12个急性病灶根本未被检测到。包括表观扩散系数的SE-DWI与EP-DWI的相关性相当好,但该检查方法不实用。
EP-DWI对早期缺血性脑卒中的诊断可靠,而SE-DWI的诊断效果也较好。传统的PD加T2加权成像对早期缺血的诊断不可靠。