Kooman J P, Leunissen K M, Luik A J
Blood Purif. 1998;16(6):301-11. doi: 10.1159/000014349.
Salt and fluid overload play an important role in the pathogenesis of hypertension in patients with end-stage renal disease. However, in the individual patient, the relation between salt loading and blood pressure response is variable and appears to be influenced by various neurohumoral regulatory mechanisms. This may also have implications for the pathogenesis of structural cardiovascular abnormalities in patients with end-stage renal disease.
盐和液体超负荷在终末期肾病患者高血压的发病机制中起重要作用。然而，在个体患者中，盐负荷与血压反应之间的关系是可变的，并且似乎受多种神经体液调节机制的影响。这也可能对终末期肾病患者结构性心血管异常的发病机制产生影响。
