Sahoo P K, Barat A, Ponniah A G
National Bureau of Fish Genetic Resources (ICAR), Lucknow, India.
Indian J Exp Biol. 1998 Oct;36(10):1041-3.
An in vivo system for differentially stained sister chromatids by incorporating 5' Bromo 2' deoxyuridine at two consecutive round of DNA replication has been developed in C. punctatus. The base line developed frequency of sister chromatid exchanges (SCEs) was found to be 0.038 SCE/chromosome. This low baseline frequency of SCEs could be useful in detecting genotoxicity of pollutants in aquatic medium.
通过在两轮连续的DNA复制过程中掺入5-溴-2'-脱氧尿苷,在斑点叉尾鮰中建立了一种对姐妹染色单体进行差异染色的体内系统。发现姐妹染色单体交换(SCEs)的基线发生频率为0.038次SCE/染色体。这种SCEs的低基线频率可用于检测水介质中污染物的遗传毒性。