系统性红斑狼疮、嗜酸性粒细胞增多症与吕弗勒心内膜炎。一种不寻常的关联。

Systemic lupus erythematosus, eosinophilia and Löffler's endocarditis. An unusual association.

作者信息

Thomeer M, Moerman P, Westhovens R, Van den Eeckhout A, Dequeker J, Demedts M

机构信息

Division of Pulmonary Diseases, University Hospital Gasthuisberg, Katholieke Universiteity Leuven, Belgium.

出版信息

Eur Respir J. 1999 Apr;13(4):930-3. doi: 10.1034/j.1399-3003.1999.13d38.x.

DOI:10.1034/j.1399-3003.1999.13d38.x

PMID:10362064

Abstract

A 24-yr-old male, known since the age of 11 to have a nonerosive arthritis and later diagnosed as having systemic lupus erythematosus (SLE), developed subacute heart failure with diffuse lung infiltrates and died suddenly after having presented a moderate hypereosinophilia for 6 months for which no other causes besides the SLE were found. A post mortem examination revealed Löffler's endocarditis (endocarditis parietalis fibroplastica) with acute pulmonary capillaritis. This represents Löffler's endocarditis in the setting of SLE. To the best of the authors' knowledge, this association has not been reported before.

摘要

一名24岁男性，自11岁起就患有非侵蚀性关节炎，后来被诊断为系统性红斑狼疮（SLE），出现亚急性心力衰竭并伴有弥漫性肺部浸润，在出现中度嗜酸性粒细胞增多6个月后突然死亡，除SLE外未发现其他病因。尸检发现有勒夫勒心内膜炎（纤维增生性心内膜炎）伴急性肺毛细血管炎。这是SLE背景下的勒夫勒心内膜炎。据作者所知，这种关联此前尚未见报道。