Primary Sjögren's syndrome and its lymphoid malignancy: a report of four cases.
作者信息
Dong Y, Zhao Y, Zeng X, Sun D
机构信息
Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China.
出版信息
Chin Med J (Engl). 1998 Mar;111(3):218-9.
PMID:10374419
Abstract
OBJECTIVE
To evaluate the incidence and spectrum of malignancy of primary Sjögren's syndrome (pSS).
METHODS
250 pSS who were followed-up in Peking Union Medical College (PUMC) Hospital were analyzed.
RESULTS
Four of them were diagnosed with histopathological findings of 2 non-Hodgkin Lymphoma, 1 AILD, 1 multiple myeloma. Two died of secondary infection while receiving chemotherapy for lymphoma, 2 remained remitted.
CONCLUSIONS
The risk factors were persistent enlargement of major salivary glands, appearance of monoclonal serum lg, and disappearance of auto antibodies.
摘要
Zotero 插件