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[顽固性癫痫的外科治疗:最新进展与未来]

[Surgical treatment for intractable epilepsy: update and future].

作者信息

Morioka T, Nishio S, Fukui M

机构信息

Departement of Neurosurgery, Faculty of Medicine, Kyushu University.

出版信息

Rinsho Shinkeigaku. 1999 Jan;39(1):73-4.

Abstract

For successful surgical treatment of intractable epilepsy, identification of the epileptogenic area and functional cortex, by using the intracranial electrodes such as subdural and depth electrodes, is important. Since 1994, via chronic subdural electrodes recording, we performed anterior temporal lobectomy with hippocampectomy for 18 patients with temporal lobe epilepsy. For 10 patients with extratemporal lobe epilepsy, cortical resection of the epileptogenic cortex was performed. For the epileptogenic cortex overlapping with functional area, we added the multiple subpial transection. Favorable postoperative seizure outcome was obtained in most of the patients. Although non-invasive presurgical evaluation modalities such as MRI, video-EEG monitoring, MEG, and FDG-PET are useful in the diagnosis of epilepsy, it is impossible to localize precisely the exact epileptogenic zone and functional cortex.

摘要

对于难治性癫痫的成功外科治疗,使用硬膜下和深部电极等颅内电极来识别致痫区和功能皮层很重要。自1994年以来,通过慢性硬膜下电极记录,我们对18例颞叶癫痫患者进行了前颞叶切除术加海马切除术。对于10例颞叶外癫痫患者,进行了致痫皮层的皮质切除术。对于与功能区重叠的致痫皮层,我们增加了多处软膜下横切术。大多数患者术后癫痫发作结果良好。尽管MRI、视频脑电图监测、MEG和FDG-PET等非侵入性术前评估方法在癫痫诊断中很有用,但不可能精确地定位确切的致痫区和功能皮层。

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