Abelev G I
Vestn Ross Akad Med Nauk. 1999(4):21-5.
The paper present a brief review of progress in cancer immunology in the past 50 years and its use in the immunodiagnosis, immunoprevention, and immunotherapy of cancer. Tumor markers have been a basis of the serological diagnosis of some tumors and the immunophenotyping of leukemia. Hepatitis B virus vaccination should reduce the incidence of hepatic cell carcinoma. Investigations have provided impetus to the design of molecular genetic anticancer vaccines which are being tested in the clinical setting.
本文简要回顾了过去50年癌症免疫学的进展及其在癌症免疫诊断、免疫预防和免疫治疗中的应用。肿瘤标志物一直是某些肿瘤血清学诊断和白血病免疫分型的基础。乙肝疫苗接种应能降低肝细胞癌的发病率。研究为分子遗传抗癌疫苗的设计提供了动力,此类疫苗正在临床环境中进行测试。