Lieberman D, Galinsky D, Fried V, Grinshpun Y, Mytlis N, Tylis R, Lieberman D
Department of Geriatrics, Soroka Medical Center, Beer-Sheva, Israel.
Int J Geriatr Psychiatry. 1999 May;14(5):325-30.
The Clock Drawing Test (CDT) is a recognized and accepted instrument for the early diagnosis of dementia in the elderly. In a prospective study we evaluated the association between the results of this test and a broad range of clinical, functional and sociodemographic variables. The study was conducted on elderly patients hospitalized for rehabilitation following stroke or hip fracture (HF) in the geriatric ward of a university hospital in southern Israel. The administration of the CDT and its scoring system were adapted from Sunderland et al. and Wolfe-Klein et al. The study was conducted on all 425 elderly patients who were hospitalized during the study period and who were capable of completing the test. Stepwise multiple regression was used to evaluate the association between the results of the CDT and the other variables. The mean CDT score (+/- SD) for the entire study population was 7.8 +/- 2.5 and 145 patients (34%) had scores of 6 or below. Of the 41 variables that were tested, significant associations with the CDT were found for the following four variables only: the Folstein minimental test (beta = 0.447, p < 0.0001), the cognition value from the admission FIM (beta = 0.252, p < 0.0001), years of education (beta = 0.183, p = 0.0001), and the patient's age (beta = -0.075, p = 0.037). The total variance of the CDT explained by these four variables (Adjusted R2) was 0.554. We conclude that in the study population there was a significant proportion of patients with low CDT scores. This score, in this population, is influenced in particular by two other measures of cognitive function and by the formal level of education, together with a weaker effect of age.
钟表绘制测试(CDT)是一种公认且被接受的用于老年人痴呆症早期诊断的工具。在一项前瞻性研究中,我们评估了该测试结果与一系列广泛的临床、功能和社会人口统计学变量之间的关联。该研究在以色列南部一家大学医院老年病房因中风或髋部骨折(HF)住院接受康复治疗的老年患者中进行。CDT的实施及其评分系统改编自桑德兰等人和沃尔夫 - 克莱因等人的方法。该研究针对研究期间住院且能够完成测试的所有425名老年患者进行。采用逐步多元回归来评估CDT结果与其他变量之间的关联。整个研究人群的CDT平均得分(±标准差)为7.8±2.5,145名患者(34%)得分在6分及以下。在测试的41个变量中,仅发现以下四个变量与CDT存在显著关联:福尔斯坦简易精神状态检查(β = 0.447,p < 0.0001)、入院时功能独立性测量(FIM)的认知值(β = 0.252,p < 0.0001)、受教育年限(β = 0.183,p = 0.0001)以及患者年龄(β = -0.075,p = 0.037)。这四个变量解释的CDT总方差(调整后R²)为0.554。我们得出结论,在研究人群中,CDT得分较低的患者占相当大的比例。在该人群中,这个得分尤其受到认知功能的另外两项测量指标、正规教育水平的影响,年龄的影响相对较弱。