人及小鼠胶原蛋白XIV基因（COL14A1）的比较细胞遗传学图谱

Comparative cytogenetic mapping of COL14A1, the gene for human and mouse collagen XIV.

作者信息

Imhof M, Trueb B

机构信息

M.E. Müller-Institute, University of Bern, Switzerland.

出版信息

Cytogenet Cell Genet. 1999;84(3-4):217-9. doi: 10.1159/000015262.

DOI:10.1159/000015262

PMID:10393435

Abstract

Utilizing the FISH technique, the gene for collagen XIV was mapped in the human and the mouse genome. The human gene (COL14A1) was assigned to chromosome bands 8q23-->q24.1. This assignment is in agreement with the localization of the undulin gene (UND), whose product has been suggested to be a variant of collagen XIV. The mouse gene (Col14a1) was assigned to chromosome 15 band D. Thus, collagen XIV represents another example of a gene that belongs to human/mouse homology group 90.

摘要

利用荧光原位杂交（FISH）技术，在人类和小鼠基因组中对胶原蛋白十四（collagen XIV）基因进行了定位。人类基因（COL14A1）被定位于染色体8q23→q24.1带。这一定位与波形蛋白基因（UND）的定位一致，有人提出波形蛋白基因的产物是胶原蛋白十四的一种变体。小鼠基因（Col14a1）被定位于15号染色体D带。因此，胶原蛋白十四代表了属于人类/小鼠同源组90的基因的另一个例子。