Blackmore C C, Ramsey S D, Mann F A, Deyo R A
Department of Radiology, University of North Carolina-Chapel Hill School of Medicine 27599-7510, USA.
Radiology. 1999 Jul;212(1):117-25. doi: 10.1148/radiology.212.1.r99jl08117.
To investigate the cost-effectiveness of computed tomography (CT) relative to radiography for cervical spine screening in trauma patients.
A decision analysis model was constructed to compare the incremental cost-effectiveness of radiography and CT as primary cervical spine screening modalities in trauma patients. Analyses were performed from a societal perspective, and probability and cost estimates from the literature and institutional experience were used. In separate cost-effectiveness analyses, hypothetical cohorts of trauma patients from three defined clinical scenarios were considered: high, moderate, and low risk for cervical spine fracture. Outcome measures included cases of paralysis prevented, total cost of screening strategies, and incremental cost-effectiveness ratios.
In high-risk patients, screening with CT is a dominant strategy that prevents cases of paralysis and saves money for society. In moderate-risk patients, screening with CT is cost-effective with reference-case assumptions and within the range of most sensitivity analyses. In the low-risk group, CT screening helps prevent cases of paralysis, but the incremental cost-effectiveness ratio is high (> $80,000 per quality-adjusted life year).
CT is the preferred cervical spine screening modality in trauma patients at high and moderate risk for cervical spine fracture.
探讨计算机断层扫描(CT)相对于X线摄影用于创伤患者颈椎筛查的成本效益。
构建决策分析模型,比较X线摄影和CT作为创伤患者颈椎初步筛查方式的增量成本效益。分析从社会角度进行,使用了文献和机构经验中的概率及成本估计。在单独的成本效益分析中,考虑了来自三种特定临床场景的假设创伤患者队列:颈椎骨折高、中、低风险。结果指标包括预防的瘫痪病例数、筛查策略的总成本以及增量成本效益比。
在高风险患者中,CT筛查是一种占优策略,可预防瘫痪病例并为社会节省资金。在中风险患者中,根据参考案例假设且在大多数敏感性分析范围内,CT筛查具有成本效益。在低风险组中,CT筛查有助于预防瘫痪病例,但增量成本效益比很高(每质量调整生命年>80,000美元)。
对于颈椎骨折高风险和中风险的创伤患者,CT是首选的颈椎筛查方式。