Yakushiji M, Fujiyoshi K, Komai K, Imamura K
Dept. of Obstetrics and Gynecology, Kurume University School of Medicine.
Gan To Kagaku Ryoho. 1999 Jun;26 Suppl 1:145-56.
Advances in many areas, including oncology-epidemiology, chemotherapy, diagnosis, surgery, radiology, and clinical research have all had a positive impact on the treatment of gynecologic malignancies, so that today we have achieved an improved quality of life concomitant with increased survival rates in patients. The improvements in therapy for gynecologic malignancies have been in diagnostic procedures, such as tumor markers, molecular biologic methods, and image analysis. Considerable progress has been made in surgical management, from focal excision of primary lesions to minimal debulking surgery after the initial chemotherapy for advanced cancer. Chemotherapy has advanced markedly after the introduction of cisplatin, and various regimens or anticancer drug-analogs of cisplatin, camptotesin, and paclitaxel have been introduced. In recent years, the quality of life of patients with malignancies has been one of the most important factors in treatment. Intensive and combination therapies will be put to greater use for gynecologic malignancy in the future.
包括肿瘤流行病学、化疗、诊断、手术、放射学和临床研究在内的许多领域的进展，都对妇科恶性肿瘤的治疗产生了积极影响，因此如今我们在提高患者生存率的同时，也改善了他们的生活质量。妇科恶性肿瘤治疗方面的改进体现在诊断程序上，如肿瘤标志物、分子生物学方法和图像分析。手术治疗取得了显著进展，从原发性病变的局部切除发展到晚期癌症初始化疗后的最小化肿瘤减灭术。自顺铂引入后，化疗有了显著进步，并且引入了各种方案或顺铂、喜树碱和紫杉醇的抗癌药物类似物。近年来，恶性肿瘤患者的生活质量一直是治疗中最重要的因素之一。未来，强化和联合治疗将更多地应用于妇科恶性肿瘤。
