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[肝脏手术中的选择性和非选择性肝门阻断]

[Selective and unselective clamping in liver surgery].

作者信息

Sano K, Takayama T, Makuuchi M

机构信息

Department of Surgery, Graduate School of Medicine, University of Tokyo, Japan.

出版信息

Nihon Geka Gakkai Zasshi. 1999 May;100(5):331-4.

Abstract

Liver surgery requires a reduction in the operative blood loss to avoid postoperative liver failure. We carried out elective hepatic resection in 229 patients with Pringle's maneuver, which involves complete, intermittent clamping of the hepatic flow, and in 56 patients with selective vascular occlusion. Twenty-seven donors for living-related liver transplantation were also included in the latter series. The clinical outcomes were evaluated based on clamping method used. The cumulative clamping time and amount of blood loss were 64 +/- 46 min (mean +/- SD) and 828 +/- 665 ml in the Pringle's maneuver group and 88 +/- 44 min and 907 +/- 555 ml in the selective vascular occlusion group. Laboratory data showed good tolerance of vascular clamping in both groups, and serum aspartate aminotransferase levels returned to the baseline within one week. Operative morbidity rates were 23% and 27%, respectively, and no operative deaths occurred in this series. In living-related liver transplantation, modified selective vascular occlusion can preserve graft viability, as verified by the fact that all the recipients in this series had a good postoperative course, except for one death and one graft loss. In conclusion, intermittent total or selective vascular clamping is indispensable procedure during hepatic resection.

摘要

肝脏手术需要减少术中失血以避免术后肝衰竭。我们对229例行普林格尔手法(即完全、间歇性阻断肝血流)的患者以及56例行选择性血管阻断的患者进行了择期肝切除术。后一组还包括27例活体肝移植供体。根据所采用的阻断方法评估临床结果。普林格尔手法组的累计阻断时间和失血量分别为64±46分钟(均值±标准差)和828±665毫升,选择性血管阻断组为88±44分钟和907±555毫升。实验室数据显示两组对血管阻断均有良好耐受性,血清天冬氨酸氨基转移酶水平在一周内恢复至基线。手术发病率分别为23%和27%,本系列中无手术死亡病例。在活体肝移植中,改良的选择性血管阻断可保存移植物活力,本系列中除1例死亡和1例移植物丢失外,所有受者术后病程良好即证实了这一点。总之,间歇性完全或选择性血管阻断是肝切除术中必不可少的步骤。

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