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[复杂型与非复杂型消化性溃疡患者红细胞功能状态的变化]

[Changes in the functional state of the erythrocytes in complicated and uncomplicated peptic ulcer].

作者信息

Kolomoiets' M Iu, Rak O L, Fartushniak L V

出版信息

Lik Sprava. 1999 Jan-Feb(1):48-51.

Abstract

Analysis of the data obtained suggests that uncontrolled intensification of processes of free-radical lipid peroxidation is a bad prognostic sign in uncomplicated peptic ulcer as is rise in the aggregation activity of erythrocytes, viscosity of blood, decline in the ability of erythrocytes to deform, particularly so in peptic ulcer complicated by acute hemorrhage. The changed erythrocytes are involved into the evolution of the vicious circle causing disturbances in the gastric and duodenal mucosa microcirculation, which fact suggest the need for correction of impaired plastic properties of erythrocytes.

摘要

对所获数据的分析表明,自由基脂质过氧化过程的失控加剧在单纯性消化性溃疡中是不良预后指标,红细胞聚集活性增加、血液黏度增加、红细胞变形能力下降也是如此,尤其是在并发急性出血的消化性溃疡中。形态改变的红细胞参与恶性循环的发展,导致胃和十二指肠黏膜微循环紊乱,这一事实表明需要纠正红细胞受损的可塑性。

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