Andrés J A, Correa N S, Rosas S B
Departamento de Ciencias Naturales, Facultad de Ciencias Exactas, Físico-Químicas y Naturales, Universidad Nacional de Río Cuarto, Pcia de Córdoba, Argentina.
Rev Argent Microbiol. 1999 Apr-Jun;31(2):82-6.
Chemical products used in agriculture require detailed formulation and knowledge on their mode of action and uses. This is essential for understanding the pesticide's biological behavior and also to establish safety criteria for humans and animals. At the present time, there are numerous studies concerning physical and chemical agents present in the media which increase the incidence of tumors. In this paper, we demonstrate the mutagenic capacity of the fungicide thiram, using the microbiological Ames test, at a concentration of 1 mg/ml active ingredient in the culture medium. Higher concentrations were lethal to the microorganisms used in the test.
农业中使用的化学产品需要详细的配方以及关于其作用方式和用途的知识。这对于理解农药的生物学行为以及建立人类和动物的安全标准至关重要。目前,有许多关于环境中存在的增加肿瘤发病率的物理和化学因子的研究。在本文中,我们使用微生物艾姆斯试验,证明了杀菌剂福美双在培养基中活性成分浓度为1毫克/毫升时的致突变能力。更高的浓度对试验中使用的微生物具有致死性。