一名患有多发性骨髓瘤、淀粉样变性和肾脏轻链沉积病且生存期较长的患者。
A patient with multiple myeloma, amyloidosis and light-chain deposition disease in kidneys with a long survival.
作者信息
Christou L, Hatzimichael E C, Sotsiou-Candila F, Siamopoulos K, Bourantas K L
机构信息
Haematology Unit, Department of Internal Medicine, Ioannina Medical School, Ioannina University, Ioannina, Greece.
出版信息
Acta Haematol. 1999;101(4):202-5. doi: 10.1159/000040954.
We report a case of a 39-year-old man with lambda-light-chain multiple myeloma, nephrotic syndrome due to lambda-light-chain deposition disease in kidneys and amyloidosis in other tissues. The patient was treated with melphalan and prednisone for 1 year. After that, he was administered interferon-alpha2b (IFN-alpha2b; 3 MU, 3 times a week) as maintenance therapy for 2 years. At present, 5 years and 6 months after the initial diagnosis, the patient receives IFN-alpha2b (3 MU, twice a week) and remains in complete haematological remission.
我们报告一例39岁男性患者，患有λ轻链多发性骨髓瘤、因肾脏λ轻链沉积病导致的肾病综合征以及其他组织的淀粉样变性。该患者接受美法仑和泼尼松治疗1年。之后，给予α-干扰素2b（IFN-α2b；3 MU，每周3次）作为维持治疗2年。目前，在初次诊断5年6个月后，患者接受IFN-α2b（3 MU，每周2次）治疗，仍处于完全血液学缓解状态。
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