Appetecchia M, Chilelli M, Sciarretta F, Anzà M
Service of Endocrinology, Regina Elena Cancer Institute, Rome, Italy.
Urol Int. 1999;62(1):37-9. doi: 10.1159/000030353.
Myelolipomas of the adrenal gland were first described in 1905. They are rare cortical, nonfunctioning, benign neoplasms, generally unilateral, usually discovered by accident or at autopsy. Thus they are often classified as 'incidentaloma'. These tumors are more frequent in males 40-60 years old. Most adrenal myelolipomas are small (diameter < 4 cm) and asymptomatic (70%), but larger tumors may cause local symptoms secondary to mechanical compression. Very large bilateral adrenal myelolipomas are exceedingly rare. They generally require no treatment; however, if symptomatics or if diagnosis is in doubt, surgery is needed. Usually only monolateral adrenalectomy is performed, even in the presence of bilateral tumors, to preserve adrenal function. We present a case of bilateral, symptomatic giant myelolipoma in a young woman, treated with bilateral adrenalectomy.
肾上腺髓质脂肪瘤于1905年首次被描述。它们是罕见的皮质、无功能的良性肿瘤,通常为单侧,多在偶然情况下或尸检时发现。因此,它们常被归类为“偶发瘤”。这些肿瘤在40至60岁的男性中更为常见。大多数肾上腺髓质脂肪瘤体积较小(直径<4cm)且无症状(70%),但较大的肿瘤可能因机械压迫而引起局部症状。双侧肾上腺巨大髓质脂肪瘤极为罕见。它们通常无需治疗;然而,如果出现症状或诊断存疑,则需要进行手术。即使存在双侧肿瘤,通常也仅进行单侧肾上腺切除术,以保留肾上腺功能。我们报告一例年轻女性双侧有症状的巨大髓质脂肪瘤,接受了双侧肾上腺切除术。