Stöllberger C, Finsterer J, Slany J
Neurologisches Krankenhaus Rosenhügel, Wien.
Z Kardiol. 1999 Jun;88(6):442-7. doi: 10.1007/s003920050307.
To evaluate 1) how many patients with atrial fibrillation (AF) and heart failure were discharged from Austrian hospitals with antithrombotic therapy, 2) if the presence of risk factors for stroke/embolism (age > 65 years, arterial hypertension, diabetes, and previous stroke) influence the choice of antithrombotic therapy and if the presence of contraindications for oral anticoagulation (dementia, alcohol abuse) influence the choice of antithrombotic therapy, and 3) if there are differences among the types of departments in the use of antithrombotic therapy.
Included were 1566 patients (841 female, 725 male, mean age 76 years) with AF and heart failure.
At discharge, a questionnaire was completed including risk factors, contraindications for antithrombotic therapy, and antithrombotic medication.
Oral anticoagulants (OAC) had 26% of the cases, acetyl salicylic acid (ASA) 31%, a combination of OAC and ASA 2%, and no antithrombotic therapy 41%. The risk factors age > 65 years, arterial hypertension, diabetes, and previous stroke did not influence the choice of antithrombotic therapy. Dementia but not alcohol abuse influenced the choice against OAC. The rate of OAC was higher in cardiological or cardiovascular rehabilitation clinics than in other departments.
The results of this survey show that in medical practice the recommendations regarding antithrombotic therapy in atrial fibrillation are rarely considered, especially when additional risk factors are present.
评估1)有多少患有心房颤动(AF)和心力衰竭的患者在奥地利医院接受抗血栓治疗出院;2)中风/栓塞风险因素(年龄>65岁、动脉高血压、糖尿病和既往中风)的存在是否会影响抗血栓治疗的选择,以及口服抗凝治疗的禁忌证(痴呆、酗酒)的存在是否会影响抗血栓治疗的选择;3)不同科室在使用抗血栓治疗方面是否存在差异。
纳入1566例患有AF和心力衰竭的患者(女性841例,男性725例,平均年龄76岁)。
出院时填写一份问卷,内容包括风险因素、抗血栓治疗的禁忌证和抗血栓药物。
口服抗凝剂(OAC)治疗的病例占26%,乙酰水杨酸(ASA)治疗的占31%,OAC与ASA联合治疗的占2%,未进行抗血栓治疗的占41%。年龄>65岁、动脉高血压、糖尿病和既往中风等风险因素不影响抗血栓治疗的选择。痴呆而非酗酒影响不选用OAC的决定。心脏病学或心血管康复诊所使用OAC的比例高于其他科室。
本次调查结果表明,在医疗实践中,关于心房颤动抗血栓治疗的建议很少被考虑,尤其是在存在其他风险因素的情况下。