[Autonomic regulation in patients with panic attacks based on longitudinal study data on the variability of the heart rhythm].

During a repeated study in recumbent position as well as during 48-hour monitoring of the indices of variability of RR intervals of ECG (MDRR) in patients with panic attacks (PA) a stable dominance of VLF (0.07-0.01 Hz) and rigidity of the spectrum typical for patients with panic attacks (PA) in period between the attacks was found. Prevalence of fear emotions as well as accompanying hypothalamic insufficiency were also associated with a decrease of HF. In prodromic period, in attack and after it, there was no dynamics in the frequency of heart's contractions, but there was a sharp increase of MDRR. In prodromic period VLF and LF considerably increased, while HF decreased. In a moment of a panic attack LF and HF continued to increase, while VLF significantly lowered. Activation of vasomotor (LF), vagal (HF) and cerebral (VLF) mechanisms was maintained during 5 minutes of the study after PA completion with a clear predominance of LF component.