Grunt J, Krcméry V, Rosival L, Calpas S
Zentralbl Bakteriol Orig A. 1978 Nov;242(2):239-44.
Results of antibiotic resistance of strains belonging to 9 species of so-called Problem bacteria, recorded by 10 District Public Health Laboratories in Slovakia during 6 months of 1977 (altogether 32641 strains) have been compared with results, obtained with identical computer-assisted system in 1973. The position of "Reserve antibiotics" (gentamicin, colistin, cotrimoxazole, oxacillin, lincomycin, spiramycin) remained favourable during precedent 4 years and even improved (with exception of gentamicin in P. aeruginosa). In classical antibiotics a typical steady-state situation was establishedin that period. Beta-lactam antibiotics in general deteriorated in gramnegatives, with certain improvements in special cases. In "specific pathogens", i.e. enteropathogenic strains of E. coli and in strains of P. aeruginosa, resistance to antibiotics generally increased. On the other hand, in S. aureus strains a better susceptibility to almost all antibiotics could be recorded. Surgical services still seem to use the bacteriological services infrequently and this should improve on an all-nation basis.
1977年6个月期间，斯洛伐克10个地区公共卫生实验室记录的9种所谓“问题细菌”菌株的抗生素耐药性结果（共32641株），已与1973年使用相同计算机辅助系统获得的结果进行了比较。“储备抗生素”（庆大霉素、黏菌素、复方新诺明、苯唑西林、林可霉素、螺旋霉素）在前4年的地位仍然有利，甚至有所改善（铜绿假单胞菌中的庆大霉素除外）。在那个时期，经典抗生素建立了典型的稳态情况。β-内酰胺类抗生素在革兰氏阴性菌中总体上有所恶化，但在某些特殊情况下有所改善。在“特定病原体”中，即大肠杆菌的肠道致病菌株和铜绿假单胞菌菌株中，对抗生素的耐药性普遍增加。另一方面，在金黄色葡萄球菌菌株中，可以记录到对几乎所有抗生素的敏感性更好。外科服务似乎仍然很少使用细菌学服务，这一点应该在全国范围内得到改善。
