Gauss A, Hübner C, Meierhenrich R, Röhm H J, Georgieff M, Schütz W
Department of Anesthesiology, University of Ulm, Germany.
Acta Anaesthesiol Scand. 1999 Aug;43(7):731-6. doi: 10.1034/j.1399-6576.1999.430708.x.
Complete heart block is dreaded perioperatively in patients with chronic bifascicular or left bundle branch block (LBBB) and additional first-degree A-V block. Our aim was to investigate the necessity as well as the efficacy and safety of transcutaneous pacing in the perioperative setting.
Thirty-nine consecutive patients with asymptomatic chronic bifascicular block or LBBB and prolongation of the P-R interval scheduled to undergo surgery under anesthesia were prospectively enrolled in the study. Preoperatively, a transcutaneous pacemaker (PACE 500 D, Osypka Co.) was applied; its efficacy was checked with intra-arterial blood pressure measurement; the pain level was recorded. Additionally, 24-h Holter monitoring (CM2, CM5) was applied. Occurrences of a block progression or a bradycardia of <40 beats/min with hemodynamic impairment were the defined end points.
Thirty-seven of the 39 patients (95%) could be successfully stimulated with a median current strength of 70 mA; whereby 33 of the 39 patients felt moderate to severe pain. There was no perioperative block progression. Three cases of brady-cardia of <40 beats/min with a critical drop in blood pressure occurred; but these patients were successfully treated with drug therapy without pacemaker stimulation.
The perioperative application and testing of the pacemaker was safe and could be performed in nearly all patients successfully. However, we do not consider a routine prophylactic transcutaneous placement in patients with chronic bifascicular or LBBB and additional first-degree A-V block justified. Nevertheless, appropriate drugs and temporary pacemaker equipment should be easily accessible.
对于患有慢性双分支阻滞或左束支传导阻滞(LBBB)且伴有一度房室传导阻滞的患者,围手术期发生完全性心脏传导阻滞令人担忧。我们的目的是研究围手术期经皮起搏的必要性、有效性和安全性。
连续39例计划在麻醉下接受手术的无症状慢性双分支阻滞或LBBB且P-R间期延长的患者前瞻性纳入本研究。术前应用经皮起搏器(PACE 500 D,Osypka公司);通过动脉内血压测量检查其有效性;记录疼痛程度。此外,应用24小时动态心电图监测(CM2、CM5)。定义的终点为阻滞进展或心率<40次/分钟且伴有血流动力学损害的心动过缓的发生情况。
39例患者中有37例(95%)能够以70 mA的中位电流强度成功刺激;其中39例患者中有33例感到中度至重度疼痛。围手术期无阻滞进展。发生3例心率<40次/分钟且血压急剧下降的心动过缓;但这些患者在未进行起搏器刺激的情况下通过药物治疗成功治愈。
围手术期起搏器的应用和测试是安全的,几乎可以在所有患者中成功进行。然而,我们认为对于患有慢性双分支阻滞或LBBB且伴有一度房室传导阻滞的患者常规预防性经皮放置起搏器不合理。尽管如此,应确保易于获得适当的药物和临时起搏器设备。