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后腹腔镜肾切除术治疗肾脏良性疾病:与开放性手术肾切除术的前瞻性非随机对照研究

Retroperitoneoscopic nephrectomy for benign diseases of the kidney: prospective nonrandomized comparison with open surgical nephrectomy.

作者信息

Hemal A K, Talwar M, Wadhwa S N, Gupta N P

机构信息

Department of Urology, All India Institute of Medical Sciences, New Delhi.

出版信息

J Endourol. 1999 Jul-Aug;13(6):425-31. doi: 10.1089/end.1999.13.425.

Abstract

PURPOSE

To describe, define, and evaluate the efficacy of retroperitoneoscopic nephrectomy (RPN) for benign diseases of the kidney and to compare it with open surgical nephrectomy (OSN) via a flank approach.

PATIENTS AND METHODS

From August 1995 to November 1997, 29 men and 14 women (mean age 33 years) with severely damaged kidneys underwent RPN. Among these, 11 patients had undergone prior surgery, 3 had chronic renal failure, and 8 patients had a percutaneous nephrostomy. The RPN was performed via three or four ports, with the kidneys being removed intact from the retroperitoneal working space. During the same period, 43 patients underwent OSN through a flank approach (extrapleural and extraperitoneal) for nonfunctioning or poorly functioning kidneys.

RESULTS

In the RPN group, two patients required conversion to OSN. The operative time and estimated blood loss ranged from 40 to 210 minutes (mean 114 minutes) and 50 to 450 mL (mean 127 mL), respectively. In the OSN group, the corresponding values were 60 to 100 minutes (mean 104 minutes) and 70 to 600 mL (mean 266 mL), respectively. The mean length of hospitalization after RPN was considerably shorter--2 to 7 days (mean 3.4 days)--than after conventional open surgery--4 to 16 days (mean 8.6 days). The incidences of minor and major complications were 21% and 5%, respectively, in the RPN group and 33% and 2% in the OSN group. The postoperative analgesic requirement was significantly less (P < 0.001) in RPN group. The interval to return to normal activity ranged from 7 to 30 days (mean 20.3 days) and 20 to 60 days (mean 32.9 days) in the RPN and OSN group, respectively, with superior performance status, cosmesis, and quality of life observed in the former group.

CONCLUSION

Retroperitoneoscopic nephrectomy is as effective as open nephrectomy for benign kidney diseases with less postoperative pain, a shorter hospital stay, earlier recuperation, and excellent cosmesis. This procedure can also be performed in patients who have undergone abdominal operations previously, in those with chronic renal failure, and in those with a percutaneous nephrostomy. The operation has become our first line of approach for benign diseases of the kidney.

摘要

目的

描述、定义并评估后腹腔镜肾切除术(RPN)治疗肾脏良性疾病的疗效,并与经侧腹入路的开放性手术肾切除术(OSN)进行比较。

患者与方法

1995年8月至1997年11月,29例男性和14例女性(平均年龄33岁)肾脏严重受损的患者接受了RPN。其中,11例患者曾接受过手术,3例患有慢性肾衰竭,8例患者有经皮肾造瘘术。RPN通过三或四个切口进行,肾脏从腹膜后工作空间完整取出。同期,43例患者因肾脏无功能或功能不良经侧腹入路(胸膜外和腹膜外)接受了OSN。

结果

在RPN组中,2例患者需要转为OSN。手术时间和估计失血量分别为40至210分钟(平均114分钟)和50至450毫升(平均127毫升)。在OSN组中,相应的值分别为60至100分钟(平均104分钟)和70至600毫升(平均266毫升)。RPN后的平均住院时间明显短于传统开放性手术后的时间——分别为2至7天(平均3.4天)和4至16天(平均8.6天)。RPN组轻微和严重并发症的发生率分别为21%和5%,OSN组分别为33%和2%。RPN组术后镇痛需求明显更少(P < 0.001)。RPN组和OSN组恢复正常活动的间隔时间分别为7至30天(平均20.3天)和20至60天(平均32.9天),前一组在功能状态、美容效果和生活质量方面表现更优。

结论

后腹腔镜肾切除术治疗肾脏良性疾病与开放性肾切除术效果相当,术后疼痛更少,住院时间更短,恢复更早,美容效果极佳。该手术也可用于既往接受过腹部手术的患者、慢性肾衰竭患者和有经皮肾造瘘术的患者。该手术已成为我们治疗肾脏良性疾病的首选方法。

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