Bauer R, Hoheisel O, Stuhlfauth I, Wolf H
Institut für Pharmazeutische Biologie der Heinrich-Heine-Universität, Düsseldorf, Deutschland.
Wien Med Wochenschr. 1999;149(8-10):185-9.
In Northamerican folk medicine Echinacea purpurea L. Moench (purple coneflower) was used as a medicinal plant. Nowadays various formulations containing stabilized or dried pressed juice from Echinacea purpurea as an active ingredient are often administered to treat common colds. These preparations are very well tolerated and safe. Allergic reactions, mainly reversible skin reactions, may occur especially in persons showing hypersensibility after contact with plants from the Compositae family. Pharmacological data let assume purple coneflower pressed juice preparations stimulate the innate immune system and increase the resistance to common colds. In this context the stimulation of the oxidative burst as well as the modulation on monokine secretion by the pressed juice of purple coneflower are reviewed. Also relevant clinical studies are presented concerning the treatment of infections respectively of common cold.
在北美民间医学中,紫松果菊(Echinacea purpurea L. Moench)被用作药用植物。如今,各种以紫松果菊的稳定化或干燥压榨汁为活性成分的制剂常被用于治疗普通感冒。这些制剂耐受性良好且安全。过敏反应,主要是可逆性皮肤反应,可能会发生,尤其是在接触菊科植物后表现出超敏反应的人群中。药理学数据表明,紫松果菊压榨汁制剂可刺激先天免疫系统并增强对普通感冒的抵抗力。在此背景下,本文综述了紫松果菊压榨汁对氧化爆发的刺激作用以及对单核因子分泌的调节作用。此外,还介绍了有关感染尤其是普通感冒治疗的相关临床研究。