Koh E T, Yap A U, Koh C K, Chee T S, Chan S P, Boudville I C
Department of Rheumatology/Immunology, Tan Tock Seng Hospital, Singapore.
J Rheumatol. 1999 Sep;26(9):1918-22.
To determine the frequency and character of temporomandibular disorders (TMD) in Oriental patients with rheumatoid arthritis (RA) and to investigate the relationship between TMD and RA in a tertiary referral center.
Symptoms and signs related to TMD were investigated in 80 patients (67 female, 13 male) who fulfilled the American College of Rheumatology 1987 revised criteria for RA. Diagnoses of TMD including muscle, disk displacement, or temporomandibular joint (TMJ) disorders were made based on clinical assessment. TMJ disorder was then correlated with the clinical, laboratory, and radiological features of RA.
The mean age of the study population was 49.7 years and the mean duration of RA was 86.9 months. Eleven patients (13.8%) had active RA at the time of TMD assessment. About 76% of the study population had seropositive disease and 62% had peripheral joint erosions. Osteoarthrosis of the TMJ was the most common TMD in this Oriental population. Joint sounds on opening (35%), joint sounds on moving sideways or forward (27.5%), and pain in jaw joints (23.7%) were common TMD symptoms. Deviated mouth opening (45%) and coarse crepitus (15-21.3%) were most prevalent on examination.
Patients with RA who had prolonged disease duration of RA and active peripheral joints tended to have osteoarthrosis of the TMJ. Presence of rheumatoid factor or peripheral joint erosions was not associated with TMJ osteoarthrosis.
确定东方类风湿关节炎(RA)患者颞下颌关节紊乱病(TMD)的发生率及特点,并在三级转诊中心研究TMD与RA之间的关系。
对80例符合美国风湿病学会1987年修订的RA标准的患者(67例女性,13例男性)进行了与TMD相关的症状和体征调查。基于临床评估对TMD进行诊断,包括肌肉、盘移位或颞下颌关节(TMJ)疾病。然后将TMJ疾病与RA的临床、实验室和放射学特征进行关联。
研究人群的平均年龄为49.7岁,RA的平均病程为86.9个月。11例患者(13.8%)在进行TMD评估时患有活动性RA。约76%的研究人群患有血清阳性疾病,62%有外周关节侵蚀。TMJ骨关节炎是该东方人群中最常见的TMD。张口时关节弹响(35%)、侧向或向前运动时关节弹响(27.5%)以及颌关节疼痛(23.7%)是常见的TMD症状。检查时张口偏斜(45%)和粗糙摩擦音(15 - 21.3%)最为普遍。
RA病程较长且外周关节活动的患者往往患有TMJ骨关节炎。类风湿因子的存在或外周关节侵蚀与TMJ骨关节炎无关。