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[生长抑制剂和激活剂处理后细胞群体动力学的准化学模型]

[Quasichemical models of dynamics of cell populations after treatment with growth inhibitors and activators].

作者信息

Ershov Iu A

机构信息

Sechenov Medical Academy of Moscow, Russia.

出版信息

Prikl Biokhim Mikrobiol. 1999 May-Jun;35(3):275-81.

Abstract

A uniform procedure is proposed, whereby growth characteristics of biological populations of various levels can be described as quantum chemistry equations. Using approaches of the kinetics of chain processes expressions have been derived, which make it possible to assess the effects of individual chemical substances and mixtures thereof on population dynamics. These expressions describe quantitatively synergistic and antagonistic effects of the substances. The models proposed describe the kinetics of growth of various populations (such as cultures of microorganisms) and can serve as a basis for targeted regulation of biotechnological processes.

摘要

提出了一种统一的方法,通过该方法可以将各级生物种群的生长特征描述为量子化学方程式。利用链式反应动力学方法推导得到了一些表达式,这些表达式使得评估单个化学物质及其混合物对种群动态的影响成为可能。这些表达式定量地描述了物质的协同和拮抗作用。所提出的模型描述了各种种群(如微生物培养物)的生长动力学,可作为生物技术过程定向调控的基础。

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