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[慢性阻塞性肺疾病(COPD)支气管扩张剂治疗的当前策略]

[Current strategy of bronchodilator therapy for chronic obstructive pulmonary disease (COPD)].

作者信息

Teramoto S

机构信息

Department of Geriatric Medicine, Tokyo University Hospital.

出版信息

Nihon Rinsho. 1999 Sep;57(9):2051-5.

Abstract

The COPD is slowly but progressive disease, the main purpose of the treatment for COPD is considered to produce a significant bronchodilating effect for maintaining lung functions for long period. Inhaled anticholinergic drug is currently used as the first-line therapy of patients with COPD. The beta 2-adrenergic agonists used be the other choice of bronchodilator for treatment of COPD. The benefit of inhalational steroid on the treatment of COPD is still a matter of debate. The accurate procedure of inhalational device and appropriate use of spacer are particularly important for older patients with COPD. The older patients with COPD can be better treated by the inhaled anticholinergic drug or its combination with beta 2-adrenergic agents.

摘要

慢性阻塞性肺疾病(COPD)是一种进展缓慢的疾病,COPD治疗的主要目的被认为是产生显著的支气管扩张作用,以长期维持肺功能。吸入性抗胆碱能药物目前被用作COPD患者的一线治疗药物。β2肾上腺素能激动剂曾是治疗COPD的支气管扩张剂的另一选择。吸入性糖皮质激素对COPD治疗的益处仍存在争议。对于老年COPD患者,吸入装置的正确操作以及储雾罐的恰当使用尤为重要。老年COPD患者使用吸入性抗胆碱能药物或其与β2肾上腺素能药物联合使用时治疗效果更佳。

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