Satou Y, Satoh N
Department of Zoology, Graduate School of Science, Kyoto University Sakyo-ku, Kyoto, 606-8502, Japan.
Curr Opin Genet Dev. 1999 Oct;9(5):542-7. doi: 10.1016/s0959-437x(99)00012-x.
The fertilized egg of ascidians develops quickly into a tadpole-type larva consisting of several distinct types of tissues including epidermis, central nervous system, endoderm, mesenchyme, notochord, and muscle. This architecture of the ascidian larva represents the most simplified chordate body plan. Taking advantage of simple, well-defined cell lineages, the expression of developmental genes is analyzed at single-cell level. Advances in the methodology promote the ascidian embryo as a useful system for studying transcriptional control involved in the specification of embryonic cells and pattern formation of the embryo.
海鞘的受精卵迅速发育成蝌蚪型幼虫,由几种不同类型的组织组成,包括表皮、中枢神经系统、内胚层、间充质、脊索和肌肉。海鞘幼虫的这种结构代表了最简化的脊索动物身体结构。利用简单、明确的细胞谱系,在单细胞水平上分析发育基因的表达。方法学的进步使海鞘胚胎成为研究参与胚胎细胞特化和胚胎模式形成的转录控制的有用系统。