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Cancer biology: extracellular proteinases in malignancy.

作者信息

Matrisian L M

机构信息

Department of Cell Biology, Vanderbilt University, Nashville, Tennessee 37232, USA.

出版信息

Curr Biol. 1999 Oct 21;9(20):R776-8. doi: 10.1016/S0960-9822(00)80011-1.

Abstract

Secreted, matrix-degrading proteinases have been viewed as contributing to tumor metastasis. A recent study indicates that the gene for one of these enzymes, the matrix metalloproteinase stromelysin-1, can actually cause cancer when expressed in transgenic mice.

摘要

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