使用气相色谱-离子阱质谱法测定动物疑似中毒病例中的聚乙醛。

Determination of metaldehyde in suspected cases of animal poisoning using gas chromatography-ion trap mass spectrometry.

作者信息

Jones A, Charlton A

机构信息

Central Science Laboratory, Ministry of Agriculture, Fisheries and Food, Sand Hutton, York Y041 1LZ, United Kingdom.

出版信息

J Agric Food Chem. 1999 Nov;47(11):4675-7. doi: 10.1021/jf990026d.

DOI:10.1021/jf990026d

PMID:10552870

Abstract

A method was developed to detect the molluscicide metaldehyde in samples of stomach contents for forensic toxicology investigations. Gas chromatography-ion trap mass spectrometry in full-scan mode was used to identify and quantify metaldehyde. The limit of detection based on mass chromatograms for the m/z 89 ion was 3 microg/g. Mean recoveries from six different spiked samples were 74% at 25 microg/g and 94% at 500 microg/g. The relative standard deviation of six replicate determinations of a sample containing 632 microg/g metaldehyde was 7.3%.

摘要

开发了一种用于法医毒理学调查的胃内容物样本中杀软体动物剂聚乙醛的检测方法。采用全扫描模式的气相色谱-离子阱质谱法对聚乙醛进行鉴定和定量。基于m/z 89离子的质量色谱图，检测限为3微克/克。六个不同加标样品的平均回收率在25微克/克时为74%，在500微克/克时为94%。对含有632微克/克聚乙醛的样品进行六次重复测定的相对标准偏差为7.3%。