二甲基亚砜和过氧化氢对组织气体张力的影响。
Effect of dimethyl sulfoxide and hydrogen peroxide on tissue gas tensions.
作者信息
Myers M B, Donovan W
出版信息
Ann N Y Acad Sci. 1975 Jan 27;243:320-4. doi: 10.1111/j.1749-6632.1975.tb25373.x.
Abstract
Tissue gas levels were measured in experimental skin flaps in rabbits, rats, and pigs. Devascularization of the flaps led to a fall in PO2 and a rise in PCO2 levels. Application of DMSO to ischemic rabbit flaps led to a fall in PCO2, DMSO and H2O2 led to a rise in PO2, an effect that lasted up to 90 min. Neither drug had an effect on the gas levels of flaps in either rats or pigs.
摘要
在兔、大鼠和猪的实验性皮瓣中测量组织气体水平。皮瓣去血管化导致氧分压（PO2）下降和二氧化碳分压（PCO2）水平升高。将二甲基亚砜（DMSO）应用于缺血的兔皮瓣导致PCO2下降，DMSO和过氧化氢（H2O2）导致PO2升高，这种作用持续长达90分钟。这两种药物对大鼠或猪皮瓣的气体水平均无影响。
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