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对未接受充分产前护理的妇女进行自愿分娩时快速艾滋病毒检测的成本效益。

The cost-effectiveness of voluntary intrapartum rapid human immunodeficiency virus testing for women without adequate prenatal care.

作者信息

Grobman W A, Garcia P M

机构信息

Section of Maternal-Fetal Medicine and the Department of Obstetrics and Gynecology, Northwestern Memorial Hospital, Northwestern University Medical School, Chicago, Illinois, USA.

出版信息

Am J Obstet Gynecol. 1999 Nov;181(5 Pt 1):1062-71. doi: 10.1016/s0002-9378(99)70082-7.

Abstract

OBJECTIVES

We sought to determine the health and economic consequences of voluntary rapid human immunodeficiency testing during labor for women who have not received adequate prenatal care.

STUDY DESIGN

A decision-tree model was used to assess the number of pediatric human immunodeficiency virus cases that would be averted if women who were unable to determine their human immunodeficiency virus serostatus antenatally were offered an intrapartum rapid human immunodeficiency virus test. Medical costs associated with the introduction of this policy were also determined. Probability and cost estimates entered into the model are based on data in the published literature.

RESULTS

Under the base-case assumptions, a policy of intrapartum voluntary rapid human immunodeficiency virus testing decreases the number of cases of perinatal human immunodeficiency virus from 407 to 339 per 100,000 women without adequate prenatal care per year, with a corresponding cost savings of $6 million. Sensitivity analysis demonstrates that these cost savings are maintained across a wide range of assumptions and that even conservative scenarios still result in a cost-effective policy.

CONCLUSIONS

In the absence of adequate prenatal care, a voluntary rapid human immunodeficiency virus test not only allows patients to fully explore their options with regard to testing and treatment but also has the potential to provide significant health benefits to women and children and economic benefits to the medical system.

摘要

目的

我们试图确定在分娩时对未接受充分产前护理的女性进行自愿快速人类免疫缺陷病毒检测的健康和经济后果。

研究设计

使用决策树模型评估,如果为产前无法确定其人类免疫缺陷病毒血清学状态的女性提供产时快速人类免疫缺陷病毒检测,可避免的儿科人类免疫缺陷病毒病例数。还确定了实施该政策的医疗成本。纳入模型的概率和成本估计基于已发表文献中的数据。

结果

在基本假设下,产时自愿快速人类免疫缺陷病毒检测政策可使每年每10万名未接受充分产前护理的女性中围产期人类免疫缺陷病毒病例数从407例降至339例,相应节省成本600万美元。敏感性分析表明,在广泛的假设范围内这些成本节省得以维持,即使是保守的情况仍会产生具有成本效益的政策。

结论

在缺乏充分产前护理的情况下,自愿快速人类免疫缺陷病毒检测不仅能让患者充分探索检测和治疗的选择,还有可能为妇女和儿童带来显著的健康益处,并为医疗系统带来经济效益。

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