Sherchand J B, Ohara H, Sherchand S, Matsuda H
Tribhuvan University Institute of Medicine, Infectious and Tropical Diseases Research Centre, Kathmandu, Nepal.
Ann Trop Med Parasitol. 1999 Apr;93(3):273-8. doi: 10.1080/00034989958537.
Eggs resembling those of Schistosoma mansoni have been observed in human stools collected from the inhabitants of Dhanusha district, in southern Nepal. In an attempt to determine if S. mansoni was present, 518 sera collected from subjects from four sites in this district were checked for antibodies to this parasite, in July 1996 and May 1997, using ELISA. Overall, 94 (18.1%) of the subjects were deemed seropositive, with the highest seroprevalence (42.7%) at the one site in Chisipani village and the lowest (1.0%) at one of the three sites in Tulaschichauda village. A follow-up study of Chisipani village, in January 1998, indicated a seroprevalence then of 22.7% (37/110). Although possible intermediate hosts, clinical manifestations and geographical distribution have yet to be explored, the present results indicate that S. mansoni probably does exist in the Dhanusha district of Nepal.
在从尼泊尔南部达努沙区居民收集的人类粪便中，发现了类似曼氏血吸虫的虫卵。为了确定是否存在曼氏血吸虫，1996年7月和1997年5月，使用酶联免疫吸附测定法（ELISA）对从该地区四个地点的受试者收集的518份血清进行了该寄生虫抗体检测。总体而言，94名（18.1%）受试者被判定为血清阳性，其中奇西帕尼村一个地点的血清阳性率最高（42.7%），图拉希乔达村三个地点之一的血清阳性率最低（1.0%）。1998年1月对奇西帕尼村进行的一项后续研究表明，当时的血清阳性率为22.7%（37/110）。尽管可能的中间宿主、临床表现和地理分布还有待探索，但目前的结果表明，尼泊尔达努沙区可能确实存在曼氏血吸虫。
