Ryvlin P, Bouvard S, Le Bars D, Mauguière F
Department of Functional Neurology and Epileptology, CERMEP, Neurological Hospital, Lyon, France.
Neurology. 1999 Nov 10;53(8):1882-5. doi: 10.1212/wnl.53.8.1882.
We have observed a falsely lateralizing mesial temporal [11C]-flumazenil binding asymmetry in three patients who had temporal lobe epilepsy (TLE) with normal hippocampal volumes. This abnormality was not detected 3 months later in two of the patients who underwent a second PET study. We conclude that transient and falsely lateralizing changes of flumazenil binding might occur in patients with TLE and no hippocampal sclerosis.