A correlative cytohistologic study on the interrelationship between exfoliated urinary bladder carcinoma cell types and the staging and grading of these tumors.

The purpose of this sutdy was to demonstrate the existence of a certain correlation between the type of exfoliated malignant tumor cells (transitional and/or epidermoid) in 28 bladder tumor cases, and the stage of these tumors as evidenced in histologic sections of full-depth bladder biopsies or cystectomies. This investigation permitted not only correlation of the type of malignant cells with the stage but also with the grade of these tumors. However, this study should be followed by more investigations based on quantitative analyses or cytomorphometric approaches in order to reach more definitive results.