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[近视患者准分子激光原位角膜磨镶术后早期视力的发育]

[Development of visual acuity in the early phase after photorefractive keratectomy in myopia].

作者信息

Nguyen N X, Langenbucher A, Walter A, Küchle M, Seitz B

机构信息

Augenklinik mit Poliklinik, Universität Erlangen-Nürnberg.

出版信息

Klin Monbl Augenheilkd. 1999 Oct;215(4):233-6. doi: 10.1055/s-2008-1034705.

Abstract

BACKGROUND

Photorefractive keratectomy (PRK) using the excimer laser is an accepted surgical technique for correction of myopic refraction errors in case of spectacle or contact lens incompatibility. The purpose of this study was to assess the development of uncorrected (UVA) and best-corrected visual acuity (CVA) in the early course following PRK.

PATIENTS AND METHODS

48 eyes of 29 patients that underwent myopic photorefractive keratectomy using 193 nm excimer laser (MEL 60, Aesculap-Meditec) were included in this study. The mean preoperative spherical equivalent was -5.3 +/- 2.4 diopters (D) (range -1.75 to -9.5 D). Pre-, intra- and postoperative treatment was standardized. The median time interval to complete epithelial closure was 2 days. According to their spherical equivalent, patients were divided in two groups: group 1 with myopia < or = 6 D (n = 28), group 2 with myopia more than 6 D (n = 20). Examination of UVA and CVA were performed preoperatively and on days 3, 7 as well as 1 month, 3 and 6 months postoperatively.

RESULTS

On day 3 after surgery UVA was 0.43 +/- 0.21 for group 1 with myopia < or = 6 D, and 0.36 +/- 0.14 for group 2 with myopia more than 6 D. The UVA was stable after 3 months (0.92 +/- 0.29 and 0.66 +/- 0.20, respectively), the CVA was stable after 1 month (1.04 +/- 0.18 and 0.86 +/- 0.19, respectively). After surgery, the UVA increased by +0.73 +/- 0.25, whereas the CVA increased by +0.05 +/- 0.10 for the whole group. The difference comparing pre- and postoperative UVA was significantly higher in group 1 (0.81 +/- 0.22) than in group 2 (0.60 +/- 0.26) (p = 0.002). However, postoperative CVA values were not significantly different from preoperative values in both groups after 6 months (p = 0.3).

CONCLUSION

Useful uncorrected visual acuity is normally achieved at day 3 after PRK in eyes with mild to moderate myopia. With higher degrees of myopia the uncorrected visual acuity does increase slower towards a lower level. One of the reasons for this phenomenon might be a significant regression of the refractive effects during the first half year after surgery.

摘要

背景

对于因眼镜或隐形眼镜不适用而需要矫正近视屈光不正的情况,使用准分子激光的光性屈光性角膜切削术(PRK)是一种被认可的手术技术。本研究的目的是评估PRK术后早期未矫正视力(UVA)和最佳矫正视力(CVA)的发展情况。

患者与方法

本研究纳入了29例接受193nm准分子激光(MEL 60,蛇牌美敦力)近视光性屈光性角膜切削术的患者的48只眼。术前平均等效球镜度数为-5.3±2.4屈光度(D)(范围-1.75至-9.5D)。术前、术中和术后治疗均标准化。上皮完全愈合的中位时间间隔为2天。根据等效球镜度数,患者分为两组:1组近视≤6D(n = 28),2组近视>6D(n = 20)。术前以及术后第3天、第7天、1个月、3个月和6个月进行UVA和CVA检查。

结果

术后第3天,近视≤6D的1组UVA为0.43±0.21,近视>6D的2组UVA为0.36±0.14。3个月后UVA稳定(分别为0.92±0.29和0.66±0.20),1个月后CVA稳定(分别为1.04±0.18和0.86±0.19)。术后,全组UVA提高了+0.73±0.25,而CVA提高了+0.05±0.10。1组术前与术后UVA的差异(0.81±0.22)显著高于2组(0.60±0.26)(p = 0.002)。然而,6个月后两组术后CVA值与术前值相比均无显著差异(p = 0.3)。

结论

轻度至中度近视患者PRK术后第3天通常可获得有用的未矫正视力。近视度数越高,未矫正视力达到较低水平的增长速度越慢。这种现象的原因之一可能是术后上半年屈光效果出现显著回退。

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