Buschbacher R M
Department of Physical Medicine and Rehabilitation, Indiana University, Indianapolis, USA.
Am J Phys Med Rehabil. 1999 Nov-Dec;78(6 Suppl):S15-20. doi: 10.1097/00002060-199911001-00004.
Tibial motor studies to the abductor hallucis are commonly performed in electrodiagnosis. Numerous authors have investigated this nerve to derive the normal ranges for latency, amplitude, and nerve conduction velocity (NCV). Many of the studies were performed without regard to temperature control, fixed distance measurement, and demographic characteristics such as age, gender, and height, which are known to affect nerve conduction studies. They often used small sample sizes, and some did not use true normal controls. This study was performed to create an expanded database of normative values for the tibial nerve. In this study, 250 asymptomatic subjects without risk factors for neuropathy were recruited and tested for their tibial motor response. Latency, amplitude, area, duration, and NCV were recorded. A repeated measures analysis of variance was performed with the waveform measures as the dependent variables and age, gender, and height as independent variables. Factors that were significant at the P < or = 0.01 level were used to create separate normative databases. Age was found to be associated with different results for amplitude, area, and NCV. Height was found to be associated with different results for NCV. Once these statistically significant factors were determined, Tukey-adjusted pair-wise comparisons of least squares means were used to collapse categories (by decade for age) that were not significantly different from each other at the P < or = 0.05 level. Side-to-side and proximal-to-distal differences were analyzed. The normal range was derived as mean +/- 2 standard deviations (SD) and at the 97th (third) percentiles of observed values. Mean onset latency was 4.5 ms (SD, 0.8). Mean amplitude was 15.3 mV (SD, 4.5), 12.9 mV (SD, 4.5), and 9.8 mV (SD, 4.2) for the respective age groups of 19-29, 30-59, and 60-79 yr. Nerve conduction velocity ranged from a mean of 44 to 51 m/s depending on the demographic groups of various ages and heights. The upper limit of side-to-side latency variation was 1.4 ms (at the 97th percentile), and the upper limit of normal amplitude difference from side to side was 50% (at the 97th percentile). The other measures are presented in the article.
在电诊断中,通常会对胫神经至拇展肌进行运动功能研究。众多作者对该神经进行了研究,以得出潜伏期、波幅和神经传导速度(NCV)的正常范围。许多研究在进行时未考虑温度控制、固定距离测量以及年龄、性别和身高等人口统计学特征,而这些因素已知会影响神经传导研究。他们常常使用小样本量,并且一些研究未使用真正的正常对照。本研究旨在创建一个更全面的胫神经正常值数据库。在这项研究中,招募了250名无神经病变危险因素的无症状受试者,并对其胫神经运动反应进行测试。记录潜伏期、波幅、面积、时限和NCV。以波形测量值作为因变量,年龄、性别和身高作为自变量进行重复测量方差分析。在P≤0.01水平具有显著性的因素用于创建单独的正常值数据库。发现年龄与波幅、面积和NCV的不同结果相关。发现身高与NCV的不同结果相关。一旦确定了这些具有统计学显著性的因素,就使用经Tukey调整的最小二乘均值成对比较来合并在P≤0.05水平彼此无显著差异的类别(按年龄的十年分组)。分析了左右差异和近端至远端差异。正常范围推导为均值±2个标准差(SD)以及观察值的第97(第三)百分位数。平均起始潜伏期为4.5毫秒(SD,0.8)。19至29岁、30至59岁和60至79岁各年龄组的平均波幅分别为15.3毫伏(SD,4.5)、12.9毫伏(SD,4.5)和9.8毫伏(SD,4.2)。神经传导速度根据不同年龄和身高的人群组在44至51米/秒之间。左右潜伏期变化的上限为1.4毫秒(在第97百分位数),左右波幅正常差异的上限为50%(在第97百分位数)。文章中给出了其他测量结果。