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沙眼致角膜瘢痕患者的穿透性角膜移植术

Penetrating keratoplasty in patients with corneal scarring due to trachoma.

作者信息

Kocak-Midillioglu I, Akova Y A, Koçak-Altintas A G, Aslan B S, Duman S

机构信息

SB Ankara Hospital, Department of Ophthalmology, Cebeci-Ankara, Turkey.

出版信息

Ophthalmic Surg Lasers. 1999 Nov-Dec;30(9):734-41.

Abstract

BACKGROUND AND OBJECTIVE

Trachoma remains the leading cause of preventable corneal blindness. The outcome of penetrating keratoplasty (PK) in these patients is usually poor because of the extensive corneal vascularization, adnexal and ocular surface problems. We evaluated the long-term results of PK in patients with corneal scarring due to trachoma.

PATIENTS AND METHODS

The fiels of 16 eyes of 13 patients who underwent PK due to late sequel of trachoma were reviewed.

RESULTS

Preoperative visual acuity ranged from light perception to finger counting levels. Preoperatively, dry-eyes, meibomian gland dysfunction, trichiasis and cicatricial entropion were treated. Over a mean postoperative follow-up of 26.1 +/- 15.6 months (range of 14-61 months), eyes required redrafting due to graft rejection and failure, and corneal ulceration (12.5%). Fourteen eyes remained clear grafts (87.5%), and 13 eyes (81.3%) achieved 0.1 or better visual acuity.

CONCLUSIONS

These results suggest that although patients with corneal scarring due to trachoma are at high risk, PK may be helpful for visual rehabilitation.

摘要

背景与目的

沙眼仍然是可预防的角膜盲的主要病因。由于广泛的角膜血管化、附属器及眼表问题,这些患者穿透性角膜移植术(PK)的预后通常较差。我们评估了因沙眼导致角膜瘢痕的患者PK的长期结果。

患者与方法

回顾了13例因沙眼晚期后遗症接受PK的患者16只眼的病历资料。

结果

术前视力范围从光感至数指。术前对干眼、睑板腺功能障碍、倒睫和瘢痕性睑内翻进行了治疗。术后平均随访26.1±15.6个月(范围14 - 61个月),因移植排斥、移植失败及角膜溃疡,有眼需要再次手术(12.5%)。14只眼移植片保持透明(87.5%),13只眼(81.3%)视力达到0.1或更好。

结论

这些结果表明,尽管因沙眼导致角膜瘢痕的患者风险较高,但PK可能有助于视力康复。

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