Herek O, Sarioğlu A, Koçer N, Tiryaki A, Akkemik B
Department of Pediatric Surgery, Pamukkale University Faculty of Medicine, Denizli, Turkey.
Eur J Pediatr Surg. 1999 Oct;9(5):337-9. doi: 10.1055/s-2008-1072277.
Cholelithiasis is uncommon in childhood and usually associated with any predisposing factors such as congenital abnormalities of biliary tract, hemolytic diseases, TPN administration and diseases of terminal ileum. Recent studies demonstrated ceftriaxone inducing reversible precipitations in gallbladder that mimic cholelithiasis. This complication is termed "biliary pseudolithiasis" or "reversible cholelithiasis". In this paper we describe a patient who developed biliary pseudolithiasis after six days of ceftriaxone therapy which completely resolved eleven days after the end of the treatment, and discuss the indication for cholecystectomy.
胆石症在儿童时期并不常见,通常与任何易感因素相关,如胆道先天性异常、溶血性疾病、全胃肠外营养的应用以及回肠末端疾病。最近的研究表明,头孢曲松可在胆囊中诱导可逆性沉淀,类似于胆石症。这种并发症被称为“胆假性结石症”或“可逆性胆石症”。在本文中,我们描述了一名患者,其在接受头孢曲松治疗六天后发生了胆假性结石症,在治疗结束后十一天完全消退,并讨论了胆囊切除术的适应证。